• Chinese red yeast rice (Monascus purpureus) for primary hyperlipidemia. A meta-analysis of randomized controlled trials 

      Grimsgaard, Sameline; Zhang, Jing; Yi, Shi; Alræk, Terje; Fønnebø, Vinjar; Liu, Jianping (Journal article; Tidsskriftartikkel; Peer reviewed, 2006-11-23)
      Extracts of Chinese red yeast rice (RYR, a traditional dietary seasoning of Monascus purpureus) contains several active ingredients including lovastatin, and several trials of its possible lipid-lowering effects have been conducted. This meta-analysis assesses the effectiveness and safety of RYR preparations on lipid modification in primary hyperlipidemia. We included randomized controlled trials ...
    • Endogenous IL-1 receptor antagonist restricts healthy and malignant myeloproliferation 

      Villatoro, Alicia; Cuminetti, Vincent; Bernal, Aurora; Torroja, Carlos; Cossío, Itziar; Benguría, Alberto; Ferré, Marc; Konieczny, Joanna; Vázquez, Enrique; Rubio, Andrea; Utnes, Peter Andree; You, Xiaona; Fenton, Christopher Graham; Paulssen, Ruth H; Zhang, Jing; Sánchez-Cabo, Fatima; Dopazo, Ana; Vik, Anders; Anderssen, Endre; Hidalgo, Andres; Arranz, Lorena (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-03)
      Here we explored the role of interleukin-1β (IL-1β) repressor cytokine, IL-1 receptor antagonist (IL-1rn), in both healthy and abnormal hematopoiesis. Low IL-1RN is frequent in acute myeloid leukemia (AML) patients and represents a prognostic marker of reduced survival. Treatments with IL-1RN and the IL-1β monoclonal antibody canakinumab reduce the expansion of leukemic cells, including CD34+ ...
    • The high prevalence of low HDL-cholesterol levels and dyslipidemia in rural populations in Northwestern China 

      Ge, Pengfei; Dong, Caixia; Ren, Xiaolan; Weiderpass, Elisabete; Zhang, Chouji; Fan, Haoqiang; Zhang, Jing; Zhang, Yongrui; Xi, Jinen (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12-07)
      Background<p> <p>Dyslipidemia is a major health problem in China and an important modifiable cardiovascular disease (CVD) risk factor. This study aimed to describe the prevalence of dyslipidemia and low high density lipoprotein cholesterol (HDL-cholesterol) and associated risk factors among adults in rural northwest China.<p> Methods<p> <p>In a cross-sectional analyses involving 2,980 adults ...